In his blistering feature film debut, director Alejando González Iñárritu (THE REVENANT, BIRDMAN) delves into the brutal backstreets of an ever-evolving Mexico City as the lives of three strangers —a young man mixed up in the gritty underground world of dogfighting, a glamorous woman who makes a living from her looks, and a mysterious down-on-his-luck assassin desperate to reconnect with his estranged daughter —interconnect in unforeseen ways after a car crash alters each of their futures in a different, often tragic way.