Hollington Drive focuses on the lives of two sisters, Theresa (Anna Maxwell Martin; Line of Duty), and her older head teacher sibling, Helen (Rachael Stirling; Wild Bill). Theresa was living a blissful middle-class existence, until a local mother turns up on her doorstep with news that her son is missing. This missing boy was friendly with Theresa's children and his disappearance makes Theresa question their recent strange behaviour. Could they somehow be involved with the disappearance? And how far will Theresa go to help them cover up their mistakes?