The first of several collaborations between cult director Jesus Franco and British producer Harry Alan Towers, this horror-tinged adventure is full of jungle action, creative murders, and violent sexual sadism. Christopher Lee portrays the mysterious Asian madman Fu Manchu, plotting world domination from his secret headquarters underneath the Amazon rainforest. Fu has discovered a rare poison which affects only men, and uses it as lipstick for ten beautiful women, who are to deliver a kiss of death to each of 10 public officials. Carl Jansen (Gotz George) and Sir Denis Nayland Smith (Richard Greene), a pair of Scotland Yard detectives, track Fu Manchu to his underground hideout and -- with the aid of Dr. Ronald Petrie (Howard Marion Crawford) -- search for the antidote to the deadly poison. Lee's wooden performance is alleviated by an amusing turn by Ricardo Palacios as a revolutionary, and a beautiful female cast. Vicente Roca and Marcelo Arroita Jauregui also appear in this entertaining, if extremely sexist, fourth entry in the Fu Manchu series. Nude torture scenes and snake attacks are featured in some of the numerous prints, running 91, 88, 82, and 61 minutes.